The efficacy and safety of fenticonazole in the treatment of mixed vaginitis

Background: Vaginitis means inflammation of the vaginal mucosa and is one most common causes for consulting to a gynecologists. Mixed-type infections are simultaneous at least two types pathogens (for example, bacteria Candida species). In treatment mixed vaginitis, broad spectrum antimicrobial therapy effective on different kinds required. Aim: The purpose this review evaluate place efficacy fenticonazole nitrate (2% cream 600 mg pessary forms) in mixed-type vaginitis. Method: Literatures were retrieved by PubMed search, using combinations pertinent keywords (e.g., fenticonazole, fungal infection, infections), without any limitations terms publication date language. Papers which assessed therapeutic tolerability patients with vaginitis selected inclusion according their relevance topic, as judged authors. Results: Fenticonazole has activity, including antifungal, antibacterial antiparasidic effects. provides significant improvement symptoms such discharge, pruritus burning associated candidal vulvovaginitis, cure rate 97.5%. addition, while 85% rates bacterial it an topical option clinical 87% vulvovaginal albicans, Gardnerella vaginalis and/ or Trichomonas vaginalis. up 90% pruritus, burning, redness, discharge edema, frequently observed its rapid onset action excellent from first days treatment. Conclusion: activity It ideal alternative high Candidal vulvovaginitis caused vaginosis vaginalis, gram (+) and/or (-) bacteria, Trichomonal these tolerability. lower against three main lactobacillus strains called Lactobacillus gasseri, jensenii crispatus found flora compared miconazole metronidazole MID rates. efficacy, safety that can be choice empirically first-line been shown fungal, various studies.